CD51 (ITGAV) (NM_002210) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218837L1V

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  • LentiORF®

Lenti ORF particles, ITGAV (Myc-DDK-tagged)-Human integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV), transcript variant 1, 200ul, >10^7 TU/mL


  View "NM_002210" in other vectors (10)

USD 1,500.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name CD51 (ITGAV) (NM_002210) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol ITGAV
Synonyms CD51; MSK8; VNRA; VTNR
Vector pLenti-C-Myc-DDK
Tag Myc-DDK
ACCN NM_002210
ORF Size 3144 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC218837).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002210.3, NP_002201.1
RefSeq Size 7037
RefSeq ORF 3147
Locus ID 3685
Cytogenetics 2q32.1
Domains FG-GAP
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
MW 115.9 kDa
Gene Summary The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

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68 Mouse Clones