IQGAP1 (NM_003870) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218549L2V

Lenti ORF particles, IQGAP1 (mGFP-tagged) - Human IQ motif containing GTPase activating protein 1 (IQGAP1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IQGAP1
• Synonyms: HUMORFA01; p195; SAR1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003870
• ORF Size: 4971 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218549).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003870.3
• RefSeq Size: 7219 bp
• RefSeq ORF: 4974 bp
• Locus ID: 8826
• UniProt ID: P46940
• Cytogenetics: 15q26.1
• Domains: IQ, RasGAP_C, WW, CH, RasGAP
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Regulation of actin cytoskeleton
• MW: 189.1 kDa
• Gene Summary: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]