T (NM_003181) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218530L1V

Lenti ORF particles, T (Myc-DDK tagged) - Human T, brachyury homolog (mouse) (T), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: T
• Synonyms: SAVA; T; TFT
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_003181
• ORF Size: 1308 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218530).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003181.2
• RefSeq Size: 2518 bp
• RefSeq ORF: 1308 bp
• Locus ID: 6862
• UniProt ID: O15178
• Cytogenetics: 6q27
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• MW: 47.3 kDa
• Gene Summary: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]