RNF20 (NM_019592) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218422L4V

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  • LentiORF®

Lenti ORF particles, RNF20 (mGFP-tagged) - Human ring finger protein 20 (RNF20), 200ul, >10^7 TU/mL



USD 1,443.00


Availability*
5 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol RNF20
Synonyms BRE1; BRE1A; hBRE1
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_019592
ORF Size 2925 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC218422).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_019592.5
RefSeq Size 3972 bp
RefSeq ORF 2928 bp
Locus ID 56254
UniProt ID Q5VTR2
Cytogenetics 9q31.1
Domains RING
Protein Families Druggable Genome
MW 113.7 kDa
Gene Summary The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.