Chloride Channel 5 (CLCN5) (NM_000084) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217750L2V

Lenti ORF particles, CLCN5 (mGFP-tagged) - Human chloride channel 5 (CLCN5), transcript variant 3, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Chloride Channel 5
• Synonyms: ClC-5; CLC5; CLCK2; DENT1; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000084
• ORF Size: 2238 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217750).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000084.1
• RefSeq Size: 3173 bp
• RefSeq ORF: 2241 bp
• Locus ID: 1184
• UniProt ID: P51795
• Cytogenetics: Xp11.23
• Domains: CBS, voltage_CLC
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• MW: 83.1 kDa
• Gene Summary: This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]