TRIM58 (NM_015431) Human Tagged ORF Clone Lentiviral Particle

SKU RC217706L2V

Lenti ORF particles, TRIM58 (mGFP-tagged) - Human tripartite motif containing 58 (TRIM58), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TRIM58
• Synonyms: BIA2
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217706).
• ACCN: NM_015431
• ORF Size: 1458 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_015431.2, NP_056246.2
• RefSeq Size: 2594 bp
• RefSeq ORF: 1461 bp
• Locus ID: 25893
• UniProt ID: Q8NG06
• Cytogenetics: 1q44
• Domains: PRY, RING, SPRY, zf-B_box
• Protein Families: Druggable Genome
• MW: 54.6 kDa
• Summary: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.[UniProtKB/Swiss-Prot Function]