TAPA1 (CD81) (NM_004356) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217508L1V

Lenti ORF particles, CD81 (Myc-DDK tagged) - Human CD81 molecule (CD81), 200ul, >10^7 TU/mL

Product Images

RC217508L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC217508L1V particle to overexpress human CD81-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TAPA1
• Synonyms: CVID6; S5.7; TAPA1; TSPAN28
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_004356
• ORF Size: 708 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217508).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004356.3
• RefSeq Size: 1497 bp
• RefSeq ORF: 711 bp
• Locus ID: 975
• UniProt ID: P60033
• Cytogenetics: 11p15.5
• Domains: transmembrane4
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: B cell receptor signaling pathway
• MW: 25.6 kDa
• Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]