AGRP (NM_001138) Human Tagged ORF Clone Lentiviral Particle
SKU
RC217144L2V
Lenti ORF particles, AGRP (mGFP-tagged) - Human agouti related protein homolog (mouse) (AGRP), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | AGRP |
Synonyms | AGRT; ART; ASIP2 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC217144).
|
ACCN | NM_001138 |
ORF Size | 396 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001138.1 |
RefSeq Size | 783 bp |
RefSeq ORF | 399 bp |
Locus ID | 181 |
UniProt ID | O00253 |
Cytogenetics | 16q22.1 |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Adipocytokine signaling pathway |
MW | 14.4 kDa |
Summary | This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009] |
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