APRT (NM_000485) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216874L3V

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  • LentiORF®

Lenti ORF particles, APRT (Myc-DDK tagged) - Human adenine phosphoribosyltransferase (APRT), transcript variant 1, 200ul, >10^7 TU/mL



USD 850.00


Availability*
6 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name APRT (NM_000485) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol APRT
Synonyms AMP; APRTD
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_000485
ORF Size 540 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC216874).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000485.2, NP_000476.1
RefSeq Size 807 bp
RefSeq ORF 543 bp
Locus ID 353
Cytogenetics 16q24.3
Domains Pribosyltran
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism
MW 19.6 kDa
Gene Summary Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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