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Prostaglandin D Synthase (PTGDS) (NM_000954) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC216795L2V
- LentiORF®
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Lenti ORF particles, PTGDS (mGFP-tagged) - Human prostaglandin D2 synthase 21kDa (brain) (PTGDS), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | mGFP |
| Symbol | Prostaglandin D Synthase |
| Synonyms | L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2 |
| Mammalian Cell Selection | None |
| Vector | pLenti-C-mGFP |
| ACCN | NM_000954 |
| ORF Size | 570 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC216795).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000954.5, NP_000945.3 |
| RefSeq Size | 837 bp |
| RefSeq ORF | 573 bp |
| Locus ID | 5730 |
| UniProt ID | P41222 |
| Cytogenetics | 9q34.3 |
| Domains | lipocalin |
| Protein Pathways | Arachidonic acid metabolism, Metabolic pathways |
| MW | 20.8 kDa |
| Gene Summary | The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008] |
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