TGF beta Receptor III (TGFBR3) (NM_003243) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216595L3V

Lenti ORF particles, TGFBR3 (Myc-DDK tagged) - Human transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TGF beta Receptor III
• Synonyms: betaglycan; BGCAN
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_003243
• ORF Size: 2553 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216595).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003243.2
• RefSeq Size: 4199 bp
• RefSeq ORF: 2556 bp
• Locus ID: 7049
• UniProt ID: Q03167
• Cytogenetics: 1p22.1
• Domains: zona_pellucida
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• MW: 93.3 kDa
• Gene Summary: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]