DPYD (NM_000110) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216374L4V

  • LentiORF®

Lenti ORF particles, DPYD (mGFP-tagged) - Human dihydropyrimidine dehydrogenase (DPYD), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,442.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol DPYD
Synonyms DHP; DHPDHASE; DPD
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_000110
ORF Size 3075 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC216374).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000110.3
RefSeq Size 4451 bp
RefSeq ORF 3078 bp
Locus ID 1806
UniProt ID Q12882
Cytogenetics 1p21.3
Domains DHOdehase, fer4
Protein Families Druggable Genome
Protein Pathways beta-Alanine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Pantothenate and CoA biosynthesis, Pyrimidine metabolism
MW 111.4 kDa
Gene Summary The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.