ARFGAP1 (NM_018209) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC215268L1V

Lenti ORF particles, ARFGAP1 (Myc-DDK tagged) - Human ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ARFGAP1
• Synonyms: ARF1GAP; HRIHFB2281
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_018209
• ORF Size: 1218 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215268).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018209.2
• RefSeq Size: 3250 bp
• RefSeq ORF: 1221 bp
• Locus ID: 55738
• UniProt ID: Q8N6T3
• Cytogenetics: 20q13.33
• Domains: ArfGap
• Protein Pathways: Endocytosis
• MW: 44.5 kDa
• Gene Summary: The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]