L Kynurenine Hydrolase (KYNU) (NM_003937) Human Tagged ORF Clone Lentiviral Particle

SKU RC214932L4V

Lenti ORF particles, KYNU (mGFP-tagged) - Human kynureninase (KYNU), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: L Kynurenine Hydrolase
• Synonyms: KYNUU; VCRL2
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214932).
• ACCN: NM_003937
• ORF Size: 1395 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003937.2
• RefSeq Size: 1688 bp
• RefSeq ORF: 1398 bp
• Locus ID: 8942
• UniProt ID: Q16719
• Cytogenetics: 2q22.2
• Protein Families: Protease
• Protein Pathways: Metabolic pathways, Tryptophan metabolism
• MW: 52.2 kDa
• Summary: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]