L Kynurenine Hydrolase (KYNU) (NM_003937) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214932L3V

Lenti ORF particles, KYNU (Myc-DDK tagged) - Human kynureninase (KYNU), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: L Kynurenine Hydrolase
• Synonyms: KYNUU; VCRL2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_003937
• ORF Size: 1395 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214932).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003937.2
• RefSeq Size: 1688 bp
• RefSeq ORF: 1398 bp
• Locus ID: 8942
• UniProt ID: Q16719
• Cytogenetics: 2q22.2
• Protein Families: Protease
• Protein Pathways: Metabolic pathways, Tryptophan metabolism
• MW: 52.2 kDa
• Gene Summary: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]