SLC22A17 (NM_016609) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214220L2V

  • LentiORF®

Lenti ORF particles, SLC22A17 (mGFP-tagged) - Human solute carrier family 22, member 17 (SLC22A17), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro

AAV Particle: DDK


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USD 1,034.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol SLC22A17
Synonyms 24p3R; BOCT; BOIT; hBOIT; NGALR; NGALR2; NGALR3
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_016609
ORF Size 1560 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC214220).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_016609.3, NP_057693.3
RefSeq Size 2344 bp
RefSeq ORF 1563 bp
Locus ID 51310
UniProt ID Q8WUG5
Cytogenetics 14q11.2
Protein Families Druggable Genome, Transmembrane
MW 55.5 kDa
Gene Summary Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.