BACH2 (NM_021813) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214061L2V

Lenti ORF particles, BACH2 (mGFP-tagged) - Human BTB and CNC homology 1, basic leucine zipper transcription factor 2 (BACH2), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC214061L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC214061L2V particle to overexpress human BACH2-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: BACH2
• Synonyms: BTBD25; IMD60
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_021813
• ORF Size: 2523 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214061).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021813.1, NP_068585.1
• RefSeq Size: 9120 bp
• RefSeq ORF: 2526 bp
• Locus ID: 60468
• UniProt ID: Q9BYV9
• Cytogenetics: 6q15
• Domains: BTB, BRLZ
• Protein Families: Druggable Genome, Transcription Factors
• MW: 92.4 kDa
• Gene Summary: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).[UniProtKB/Swiss-Prot Function]