GLUT4 (SLC2A4) (NM_001042) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213717L2V

Lenti ORF particles, SLC2A4 (mGFP-tagged) - Human solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), 200ul, >10^7 TU/mL

Product Images

RC213717L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC213717L2V particle to overexpress human SLC2A4-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: GLUT4
• Synonyms: GLUT4
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001042
• ORF Size: 1527 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213717).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001042.1
• RefSeq Size: 2128 bp
• RefSeq ORF: 1530 bp
• Locus ID: 6517
• UniProt ID: P14672
• Cytogenetics: 17p13.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Insulin signaling pathway, Type II diabetes mellitus
• MW: 54.6 kDa
• Gene Summary: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]