RPS6KA3 (NM_004586) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC213645L3V
- LentiORF®
Lenti ORF particles, RPS6KA3 (Myc-DDK tagged) - Human ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK mGFP mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | RPS6KA3 |
Synonyms | CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; p90-RSK2; pp90RSK2; RSK; RSK2; S6K-alpha3 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_004586 |
ORF Size | 2220 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213645).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004586.2 |
RefSeq Size | 7723 bp |
RefSeq ORF | 2223 bp |
Locus ID | 6197 |
UniProt ID | P51812 |
Cytogenetics | Xp22.12 |
Domains | pkinase, S_TK_X, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation |
MW | 83.7 kDa |
Gene Summary | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] |
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