PADI1 (NM_013358) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC213501L4V
- LentiORF®
Lenti ORF particles, PADI1 (mGFP-tagged) - Human peptidyl arginine deiminase, type I (PADI1), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | PADI1 |
Synonyms | HPAD10; PAD1; PDI; PDI1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_013358 |
ORF Size | 1989 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213501).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013358.1 |
RefSeq Size | 3847 bp |
RefSeq ORF | 1992 bp |
Locus ID | 29943 |
UniProt ID | Q9ULC6 |
Cytogenetics | 1p36.13 |
MW | 74.7 kDa |
Gene Summary | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] |
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