Tau (MAPT) (NM_005910) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213312L2V

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  • LentiORF®

Lenti ORF particles, MAPT (mGFP-tagged) - Human microtubule-associated protein tau (MAPT), transcript variant 2, 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol MAPT
Synonyms DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; tau-40
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_005910
ORF Size 1323 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC213312).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_005910.3
RefSeq Size 5731 bp
RefSeq ORF 1326 bp
Locus ID 4137
UniProt ID P10636
Cytogenetics 17q21.31
Domains tubulin-binding
Protein Families Druggable Genome
Protein Pathways Alzheimer's disease, MAPK signaling pathway
MW 45.7 kDa
Gene Summary This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
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