Tau (MAPT) (NM_005910) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213312L2V

Lenti ORF particles, MAPT (mGFP-tagged) - Human microtubule-associated protein tau (MAPT), transcript variant 2, 200ul, >10^7 TU/mL

Product Images

RC213312L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC213312L2V particle to overexpress human MAPT-mGFP fusion protein.

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  RC213312L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC213312L2V particle to overexpress human MAPT-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MAPT
• Synonyms: DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; tau-40
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_005910
• ORF Size: 1323 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213312).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005910.3
• RefSeq Size: 5731 bp
• RefSeq ORF: 1326 bp
• Locus ID: 4137
• UniProt ID: P10636
• Cytogenetics: 17q21.31
• Domains: tubulin-binding
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, MAPK signaling pathway
• MW: 45.7 kDa
• Gene Summary: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]