KCNQ2 (NM_172107) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212932L4V

  • LentiORF®

Lenti ORF particles, KCNQ2 (mGFP-tagged) - Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,747.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol KCNQ2
Synonyms BFNC; DEE7; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_172107
ORF Size 2616 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC212932).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_172107.2
RefSeq Size 3251 bp
RefSeq ORF 2619 bp
Locus ID 3785
UniProt ID O43526
Cytogenetics 20q13.33
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane
MW 95.7 kDa
Gene Summary The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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