WNT10B (NM_003394) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212840L2V

Lenti ORF particles, WNT10B (mGFP-tagged) - Human wingless-type MMTV integration site family, member 10B (WNT10B), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: WNT10B
• Synonyms: SHFM6; STHAG8; WNT-12
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003394
• ORF Size: 1167 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212840).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003394.2
• RefSeq Size: 2288 bp
• RefSeq ORF: 1170 bp
• Locus ID: 7480
• UniProt ID: O00744
• Cytogenetics: 12q13.12
• Domains: wnt
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway
• MW: 43 kDa
• Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]