Muscarinic Acetylcholine Receptor M3 (CHRM3) (NM_000740) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212436L1V

Lenti ORF particles, CHRM3 (Myc-DDK tagged) - Human cholinergic receptor, muscarinic 3 (CHRM3), 200ul, >10^7 TU/mL

Product Images

RC212436L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC212436L1V particle to overexpress human CHRM3-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Muscarinic Acetylcholine Receptor M3
• Synonyms: EGBRS; HM3; PBS
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000740
• ORF Size: 1770 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212436).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000740.2
• RefSeq Size: 2757 bp
• RefSeq ORF: 1773 bp
• Locus ID: 1131
• UniProt ID: P20309
• Cytogenetics: 1q43
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
• MW: 65.9 kDa
• Gene Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]