ROR gamma (RORC) (NM_001001523) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212239L3V

Lenti ORF particles, RORC (Myc-DDK tagged) - Human RAR-related orphan receptor C (RORC), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ROR gamma
• Synonyms: IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001001523
• ORF Size: 1491 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212239).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001001523.1
• RefSeq Size: 3054 bp
• RefSeq ORF: 1494 bp
• Locus ID: 6097
• UniProt ID: P51449
• Cytogenetics: 1q21.3
• Protein Families: Druggable Genome, Transcription Factors
• MW: 55.6 kDa
• Gene Summary: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]