MLH3 (NM_014381) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212150L1V

  • LentiORF®

Lenti ORF particles, MLH3 (Myc-DDK tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2 , 200ul, >10^7 TU/mL

  View "NM_014381" in other vectors (10)

USD 1,250.00


Availability*
6 Weeks

Size
    • 200 ul


Product images

Specifications

Product Data
Product Name MLH3 (NM_014381) Human Tagged ORF Clone Lentiviral Particle
Symbol MLH3
Synonyms HNPCC7; HNPCC7
Vector pLenti-C-Myc-DDK
ACCN NM_014381
ORF Size 4287 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC212150).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_014381.1, NP_055196
RefSeq Size 4895
RefSeq ORF 4290
Locus ID 27030
Cytogenetics 14q24.3
Domains HATPase_c
Protein Families Druggable Genome
Protein Pathways Mismatch repair
MW 160.8 kDa
Gene Summary This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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