RIC8 (RIC8A) (NM_021932) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211359L1V

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  • LentiORF®

Lenti ORF particles, RIC8A (Myc-DDK tagged) - Human resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) (RIC8A), 200ul, >10^7 TU/mL



USD 1,050.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol RIC8A
Synonyms RIC8
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_021932
ORF Size 1611 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC211359).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_021932.4
RefSeq Size 2714 bp
RefSeq ORF 1614 bp
Locus ID 60626
UniProt ID Q9NPQ8
Cytogenetics 11p15.5
MW 60.2 kDa
Gene Summary Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.[UniProtKB/Swiss-Prot Function]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.