GLP1R (NM_002062) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211333L2V

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  • LentiORF®

Lenti ORF particles, GLP1R (mGFP-tagged) - Human glucagon-like peptide 1 receptor (GLP1R), 200ul, >10^7 TU/mL



USD 1,236.00

3 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol GLP1R
Synonyms GLP-1; GLP-1-R; GLP-1R
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_002062
ORF Size 1389 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC211333).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002062.2
RefSeq Size 3071 bp
RefSeq ORF 1392 bp
Locus ID 2740
UniProt ID P43220
Cytogenetics 6p21.2
Protein Families Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
MW 52.8 kDa
Gene Summary This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.