NLRP10 (NM_176821) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211215L2V

Lenti ORF particles, NLRP10 (mGFP-tagged) - Human NLR family, pyrin domain containing 10 (NLRP10), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: NLRP10
• Synonyms: CLR11.1; NALP10; NOD8; PAN5; PYNOD
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_176821
• ORF Size: 1965 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211215).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_176821.3
• RefSeq Size: 2020 bp
• RefSeq ORF: 1968 bp
• Locus ID: 338322
• UniProt ID: Q86W26
• Cytogenetics: 11p15.4
• MW: 75 kDa
• Gene Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]