Caspr2(CNTNAP2) (NM_014141) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210836L4V

Lenti ORF particles, CNTNAP2 (mGFP-tagged) - Human contactin associated protein-like 2 (CNTNAP2), 200ul, >10^7 TU/mL

  • LentiORF®

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USD 1,360.00


Availability*
7 Weeks

Size
    • 200 ul

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Specifications

Product Data
Product Name Caspr2(CNTNAP2) (NM_014141) Human Tagged ORF Clone Lentiviral Particle
Symbol CNTNAP2
Synonyms AUTS15; CASPR2; CDFE; NRXN4; PTHSL1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_014141
ORF Size 3993 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC210836).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_014141.4, NP_054860
RefSeq Size 9890
RefSeq ORF 3996
Locus ID 26047
Cytogenetics 7q35-q36.1
Domains F5_F8_type_C, LamG, EGF
Protein Families Transmembrane, Druggable Genome
Protein Pathways Cell adhesion molecules (CAMs)
MW 148 kDa
Gene Summary This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.