CLEC4G (NM_198492) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210798L3V

Lenti ORF particles, CLEC4G (Myc-DDK tagged) - Human C-type lectin domain family 4, member G (CLEC4G), 200ul, >10^7 TU/mL

Product Images

RC210798L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC210798L3V particle to overexpress human CLEC4G-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CLEC4G
• Synonyms: DTTR431; LP2698; LSECtin; UNQ431
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_198492
• ORF Size: 879 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210798).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_198492.1
• RefSeq Size: 1355 bp
• RefSeq ORF: 882 bp
• Locus ID: 339390
• UniProt ID: Q6UXB4
• Cytogenetics: 19p13.2
• Protein Families: Druggable Genome, Transmembrane
• MW: 32.4 kDa
• Gene Summary: This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020]