Thyroid Peroxidase (TPO) (NM_000547) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210659L1V

  • LentiORF®

Lenti ORF particles, TPO (Myc-DDK tagged) - Human thyroid peroxidase (TPO), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,404.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol Thyroid Peroxidase
Synonyms MSA; TDH2A; TPX
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_000547
ORF Size 2799 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC210659).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000547.3
RefSeq Size 3152 bp
RefSeq ORF 2802 bp
Locus ID 7173
UniProt ID P07202
Cytogenetics 2p25.3
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Metabolic pathways, Tyrosine metabolism
MW 102.9 kDa
Gene Summary This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

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