NIPP1 (PPP1R8) (NM_138558) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC210575L4V
- LentiORF®
Lenti ORF particles, PPP1R8 (mGFP-tagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | NIPP1 |
Synonyms | ARD-1; ARD1; NIPP-1; NIPP1; PRO2047 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_138558 |
ORF Size | 1056 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC210575).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_138558.1 |
RefSeq Size | 2659 bp |
RefSeq ORF | 630 bp |
Locus ID | 5511 |
UniProt ID | Q12972 |
Cytogenetics | 1p35.3 |
Protein Families | Druggable Genome, Transcription Factors |
MW | 38.5 kDa |
Gene Summary | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] |
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