MC2 receptor (MC2R) (NM_000529) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210483L2V

Lenti ORF particles, MC2R (mGFP-tagged) - Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MC2 receptor
• Synonyms: ACTHR
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000529
• ORF Size: 891 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210483).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000529.2, NP_000520.1
• RefSeq Size: 3652 bp
• RefSeq ORF: 894 bp
• Locus ID: 4158
• UniProt ID: Q01718
• Cytogenetics: 18p11.21
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• MW: 33.9 kDa
• Gene Summary: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]