PD1 (PDCD1) (NM_005018) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210364L3V

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  • LentiORF®

Lenti ORF particles, PDCD1 (Myc-DDK tagged) - Human programmed cell death 1 (PDCD1), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
2 Weeks

Size
    • 200 ul


Product images

Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol PDCD1
Synonyms CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_005018
ORF Size 864 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC210364).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_005018.1
RefSeq Size 2115 bp
RefSeq ORF 867 bp
Locus ID 5133
UniProt ID Q15116
Cytogenetics 2q37.3
Domains ig, IGv, IG
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), T cell receptor signaling pathway
MW 31.6 kDa
Gene Summary Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
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