MMP3 (NM_002422) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210235L2V

Lenti ORF particles, MMP3 (mGFP-tagged) - Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MMP3
• Synonyms: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_002422
• ORF Size: 1431 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210235).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002422.3
• RefSeq Size: 1828 bp
• RefSeq ORF: 1434 bp
• Locus ID: 4314
• UniProt ID: P08254
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome, Protease
• MW: 54 kDa
• Gene Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]