12 Lipoxygenase (ALOX12) (NM_000697) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210211L2V

Lenti ORF particles, ALOX12 (mGFP-tagged) - Human arachidonate 12-lipoxygenase (ALOX12), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: 12 Lipoxygenase
• Synonyms: 12-LOX; 12S-LOX; LOG12
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000697
• ORF Size: 1989 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210211).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000697.1
• RefSeq Size: 2335 bp
• RefSeq ORF: 1992 bp
• Locus ID: 239
• UniProt ID: P18054
• Cytogenetics: 17p13.1
• Protein Families: Druggable Genome
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways
• MW: 75.5 kDa
• Gene Summary: This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]