EIF4B (NM_001417) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209955L1V

Lenti ORF particles, EIF4B (Myc-DDK tagged) - Human eukaryotic translation initiation factor 4B (EIF4B), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: EIF4B
• Synonyms: EIF-4B; PRO1843
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001417
• ORF Size: 1833 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209955).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001417.3, NP_001408.2
• RefSeq Size: 3885 bp
• RefSeq ORF: 1836 bp
• Locus ID: 1975
• UniProt ID: P23588
• Cytogenetics: 12q13.13
• Domains: RRM
• Protein Pathways: mTOR signaling pathway
• MW: 69 kDa
• Gene Summary: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.[UniProtKB/Swiss-Prot Function]