C6orf106 (ILRUN) (NM_024294) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209929L3V

Lenti ORF particles, C6orf106 (Myc-DDK tagged) - Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ILRUN
• Synonyms: C6orf106; dJ391O22.4; FP852
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_024294
• ORF Size: 894 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209929).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024294.2
• RefSeq Size: 4433 bp
• RefSeq ORF: 897 bp
• Locus ID: 64771
• UniProt ID: Q9H6K1
• Cytogenetics: 6p21.31
• MW: 32.9 kDa
• Gene Summary: Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199).[UniProtKB/Swiss-Prot Function]