Aryl hydrocarbon Receptor (AHR) (NM_001621) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209832L2V

Lenti ORF particles, AHR (mGFP-tagged) - Human aryl hydrocarbon receptor (AHR), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Aryl hydrocarbon Receptor
• Synonyms: bHLHe76; RP85
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001621
• ORF Size: 2544 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209832).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001621.2
• RefSeq Size: 6247 bp
• RefSeq ORF: 2547 bp
• Locus ID: 196
• UniProt ID: P35869
• Cytogenetics: 7p21.1
• Domains: PAS, HLH, PAC
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• MW: 96.1 kDa
• Gene Summary: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]