HDAC6 (NM_006044) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209649L2V

Lenti ORF particles, HDAC6 (mGFP-tagged) - Human histone deacetylase 6 (HDAC6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: HDAC6
• Synonyms: CPBHM; HD6; JM21; PPP1R90
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_006044
• ORF Size: 3645 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209649).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006044.2
• RefSeq Size: 4099 bp
• RefSeq ORF: 3648 bp
• Locus ID: 10013
• UniProt ID: Q9UBN7
• Cytogenetics: Xp11.23
• Domains: Hist_deacetyl, zf-UBP
• Protein Families: Druggable Genome, Transcription Factors
• MW: 131.2 kDa
• Gene Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]