GRP94 (HSP90B1) (NM_003299) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209563L3V

Lenti ORF particles, HSP90B1 (Myc-DDK tagged) - Human heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GRP94
• Synonyms: ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_003299
• ORF Size: 2409 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209563).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003299.1
• RefSeq Size: 2879 bp
• RefSeq ORF: 2412 bp
• Locus ID: 7184
• UniProt ID: P14625
• Cytogenetics: 12q23.3
• Domains: HSP90, HATPase_c
• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer
• MW: 92.5 kDa
• Gene Summary: This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]