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Hexokinase II (HK2) (NM_000189) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209482L3V
- LentiORF®
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Lenti ORF particles, HK2 (Myc-DDK tagged) - Human hexokinase 2 (HK2), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK mGFP mGFP w/ Puro
Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | Myc-DDK |
| Symbol | Hexokinase II |
| Synonyms | HKII; HXK2 |
| Mammalian Cell Selection | Puromycin |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_000189 |
| ORF Size | 2751 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209482).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000189.4 |
| RefSeq Size | 7109 bp |
| RefSeq ORF | 2754 bp |
| Locus ID | 3099 |
| UniProt ID | P52789 |
| Cytogenetics | 2p12 |
| Domains | hexokinase |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus |
| MW | 102.2 kDa |
| Gene Summary | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009] |
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