IL27 (NM_145659) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209337L2V

Lenti ORF particles, IL27 (mGFP-tagged) - Human interleukin 27 (IL27), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IL27
• Synonyms: IL-27; IL-27A; IL27A; IL27p28; IL30; p28
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_145659
• ORF Size: 729 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209337).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_145659.3, NP_663634.2
• RefSeq Size: 1044 bp
• RefSeq ORF: 732 bp
• Locus ID: 246778
• UniProt ID: Q8NEV9
• Cytogenetics: 16p12.1-p11.2
• Protein Families: Druggable Genome, Transmembrane
• MW: 27.5 kDa
• Gene Summary: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]