GRK5 (NM_005308) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209137L4V

Lenti ORF particles, GRK5 (mGFP-tagged) - Human G protein-coupled receptor kinase 5 (GRK5), 200ul, >10^7 TU/mL

Product Images

RC209137L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC209137L4V particle to overexpress human GRK5-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: GRK5
• Synonyms: FP2025; GPRK5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005308
• ORF Size: 1770 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209137).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005308.2
• RefSeq Size: 2575 bp
• RefSeq ORF: 1773 bp
• Locus ID: 2869
• UniProt ID: P34947
• Cytogenetics: 10q26.11
• Domains: RGS, pkinase, S_TK_X, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Chemokine signaling pathway, Endocytosis
• MW: 67.8 kDa
• Gene Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008]