ICOS Ligand (ICOSLG) (NM_015259) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208975L2V

Lenti ORF particles, ICOSLG (mGFP-tagged) - Human inducible T-cell co-stimulator ligand (ICOSLG), 200ul, >10^7 TU/mL

Product Images

RC208975L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC208975L2V particle to overexpress human ICOSLG-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: ICOS Ligand
• Synonyms: B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_015259
• ORF Size: 906 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208975).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015259.4
• RefSeq Size: 3320 bp
• RefSeq ORF: 909 bp
• Locus ID: 23308
• UniProt ID: O75144
• Cytogenetics: 21q22.3
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• MW: 33.3 kDa
• Gene Summary: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).[UniProtKB/Swiss-Prot Function]