LRRC8A (NM_019594) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208632L2V

Lenti ORF particles, LRRC8A (mGFP-tagged) - Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: LRRC8A
• Synonyms: AGM5; HsLRRC8A; LRRC8; SWELL1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_019594
• ORF Size: 2430 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208632).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019594.2
• RefSeq Size: 4368 bp
• RefSeq ORF: 2433 bp
• Locus ID: 56262
• UniProt ID: Q8IWT6
• Cytogenetics: 9q34.11
• Protein Families: Transmembrane
• MW: 94.2 kDa
• Gene Summary: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]