Cullin 3 (CUL3) (NM_003590) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208066L1V

  • LentiORF®

Lenti ORF particles, CUL3 (Myc-DDK tagged) - Human cullin 3 (CUL3), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,605.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol Cullin 3
Synonyms CUL-3; NEDAUS; PHA2E
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_003590
ORF Size 2304 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC208066).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003590.2
RefSeq Size 6790 bp
RefSeq ORF 2307 bp
Locus ID 8452
UniProt ID Q13618
Cytogenetics 2q36.2
Domains CULLIN
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis
MW 88.9 kDa
Gene Summary This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

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