NFkB Inducing Kinase NIK (MAP3K14) (NM_003954) Human Tagged ORF Clone Lentiviral Particle

SKU RC207616L3V

Lenti ORF particles, MAP3K14 (Myc-DDK tagged) - Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: NFkB Inducing Kinase NIK
• Synonyms: FTDCR1B; HS; HSNIK; NIK
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207616).
• ACCN: NM_003954
• ORF Size: 2841 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003954.1
• RefSeq Size: 4596 bp
• RefSeq ORF: 2844 bp
• Locus ID: 9020
• UniProt ID: Q99558
• Cytogenetics: 17q21.31
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, T cell receptor signaling pathway
• MW: 103.9 kDa
• Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]