GPNMB (NM_001005340) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207615L4V

  • LentiORF®

Lenti ORF particles, GPNMB (mGFP-tagged) - Human glycoprotein (transmembrane) nmb (GPNMB), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,348.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol GPNMB
Synonyms HGFIN; NMB; PLCA3
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001005340
ORF Size 1716 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC207615).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001005340.1, NP_001005340.1
RefSeq Size 2775 bp
RefSeq ORF 1719 bp
Locus ID 10457
UniProt ID Q14956
Cytogenetics 7p15.3
Protein Families Druggable Genome, Transmembrane
MW 63.92 kDa
Gene Summary The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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